THREONINE DEAMINATION IN ESCHERICHIA COLI I
نویسندگان
چکیده
منابع مشابه
Formation of biodegradative threonine deaminase in Escherichia coli.
Studies were carried out on the formation of biodegradative L-threonine deaminase (EC 4.2.1.16) in resting cells of Escherichia coli. The results obtained are as follows: (1) The enzyme level was increased by adding L-threonine together with yeast extract to the cell suspension. (2) In the course of the enzyme formation, the addition of chloramphenicol or glucose to the medium resulted in insta...
متن کاملProduction of L-threonine by auxotrophic mutants of Escherichia coli.
Two auxotrophic mutants of Escherichia coli have been shown to accumulate significant amounts of l-threonine in the culture medium. One mutant, 13071, is deficient in alpha,epsilon-diaminopimelic acid (DAP), and the other, 13070, is deficient in both DAP and methionine. Accumulation of l-threonine by 13071 in a synthetic medium with mannitol as the carbon source at 37 C incubation temperature w...
متن کاملNucleotide Activation of Threonine Deaminase from Escherichia Coli.
Two distinctly different L-threonine deaminases are known to be formed in Escherichia coli. One of them participates in the biosynthesis of L-isoleucine from L-threonine and is susceptible to an end product inhibition by the former compound (1). The other one seems to participate in the catabolism of L-threonine under anaerobic conditions and is activated by adenosine 5’monophosphate (1, 2). Li...
متن کاملSystems metabolic engineering of Escherichia coli for L-threonine production
Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by systems metabolic engineering. Feedback inhibitions of aspartokinase I and III (encoded by thrA a...
متن کاملGenome sequence of Escherichia coli XH140A, which produces L-threonine.
Here we report the draft annotated genome sequence of Escherichia coli XH140A, which is used to produce l-threonine in industry. The genome sequence will allow the characterization of the molecular mechanisms underlying its beneficial properties.
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1956
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.71.4.443-449.1956